Regexil® New Formula 30 tablets

Rating: 4,0 | 2 Reviews

Regexil® New Formula 30 tablets

Rating: 4,0 | 2 Reviews
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Expires on (dd/mm/yyyy) 31/12/2024


Yamamoto® Nutrition Regexil® is a food supplement based on melatonin with valerian, passion flower and chamomile, with GABA, Escolzia and Saffron, indicated for adults.

Diet and training are the key factors of the successful athlete, but sleep is certainly another crucial element, which is often critical for the athlete, especially during the high psychophysical stress intensification phases of a preparation. In these delicate moments, many athletes encounter difficulties both in falling asleep and in sleeping or resting adequately. This can have large-scale repercussions for an athlete from influencing poor muscle recovery, increased inflammation, unfavorable insulin sensitivity, an inefficient immune system, poor concentration and greater susceptibility to trauma. Per every bodybuilder, therefore, sleep is almost essential, because it affects many factors, from muscle to metabolic, endocrine as well as on pain sensitivity. Hundreds of studies demonstrate the tangible relationship between sleep and athletic performance: metabolic, respiratory, cardiovascular and motor capacities are all negatively impacted when rest is not enough.

What is Regexil®

The Yamamoto® Nutrition Flex Series line wanted to take into consideration all the essential aspects for the athlete, and the sleep factor could not be overlooked . Thus was born Regexil ®, one of the best products on the market effective in promoting falling asleep and the quality of sleep, formulated with a highly synergistic blend of valerian extract, passion flower, chamomile, escholzia, saffron Saff'Activ ® , GABA and melatonin.

The dry extract of Valerianit contains numerous compounds (such as valepotriates, lignans, alkaloids and essential oil containing valerenic acids) with a sedative, calming, spasmolytic and muscle relaxant action, capable of reducing anxiety and counteracting stress, also promoting the induction of sleep. These compounds act on GABAergic control mainly through the inhibition of the degradation and presynaptic reuptake of the inhibitory neurotransmitter GABA and the promotion of its synthesis. Therefore, precisely because GABA has an inhibitory action, these substances which increase the activity of the GABAergic synapses depress the activity of the central nervous system, with the desired relaxing and anxiolytic effect.

The Passionflowerit is one of the most used herbal and phytotherapeutic remedies to counteract anxiety and insomnia. Its calming and sedative effect is attributed to the flavonoids and to the many other components that the extract contains (such as alkaloids, phytosterols, phenolic acids, coumarins, heterosides, cyanogenic acids). Passiflora is also used to induce muscle relaxation thanks to its spasmodic and relaxing action on the nervous system which, in synergy with Chamomile, exerts a beneficial action not only on the nervous system, but also on the digestive system and on the immune system. performing anti-inflammatory and carminative properties.

Saffron is a spice known for its use in the kitchen, but also used in traditional medicine since ancient times to improve mood. The Saffr'Activ® patent provides bioactive compounds known for their mood-enhancing action. Saffron is in fact able to influence the levels of serotonin in our body. Serotonin is a hormone that affects mood, satiety, appetite, compulsiveness and anxiety, and saffron has been shown in several studies to inhibit the reuptake of serotonin by blocking its transporter SERT: in this way released more serotonin in the brain, and this participates in the induction of a state of well-being and good mood.

Escolzia aqueous extract , obtained from the Californian plant Eschscholtzia californica, contains various molecules with biological activity such as flavonoids, carotenoids and alkaloids. The alkaloids themselves, and in particular californidine and protropine, act by exerting a sedative action on the central nervous system: they can induce sleep and have an anxiolytic effect. Several studies have confirmed the sedative properties of this plant, which has been used in folk medicine for centuries to treat insomnia and reduce agitation. Its action therefore allows you to sleep better and promote relaxation not only of the body but also of the mind.

The main function of γ-aminobutyric acid or GABAas an inhibitory neurotransmitter is to slow down brain activity. This neurotransmitter is involved in several aspects: vision, sleep, muscle tone and motor control. Its action is therefore not only aimed at the nervous system, but must also be extended to the intestine, stomach, bladder, lungs, liver, skin, spleen, muscles, kidneys, pancreas and reproductive organs. One of the most important functions of γ-aminobutyric acid is its ability to reduce stress and anxiety. When its levels are low, the chances of feeling anxious, tired and highly sensitive to stimuli increase. GABA therefore completes the Regexil® formula, increasing brain waves associated with a state of relaxation (called alpha waves) and decreasing those associated with stress and anxiety (beta waves).

In a powerful blend to counteract sleep problems, the well-known Melatonin could not be missing , an indispensable element for rebalancing the circadian rhythms in our body. Melatonin, also known as the "sleep hormone", not only acts as a regulator, but also directly induces sleep in those suffering from phase delay syndrome (DSP) or initial insomnia. In fact, these subjects find it difficult to fall asleep: in these cases melatonin favors the shortening of the times of falling asleep, without however modifying the architecture of sleep, and consequently not altering the balance between the alternation of the times of the N-REM phases and REM ones.

The effectiveness of REGEXIL ®it is further emphasized thanks to the fact that the elements it contains are inserted in a latest generation triple-layer tablet, characterized by a differentiated release technology, chosen to optimize the gradual and targeted release of each individual element over time.

Benefits of our supplement

Why choose Regexil ® :

  • Promotes relaxation;
  • Counteracts stress;
  • Promotes good mood and mental well-being;
  • Helps fight anxiety and insomnia;
  • Reduces the time it takes to fall asleep;
  • Functional triple layer tablet for the gradual release of the active ingredients.

When and how to take it

Take one tablet a day with water, preferably 30 minutes before bedtime.


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Bent S, Padula A, Moore D, Patterson M, Mehling W. Valerian for sleep: a systematic review and meta-analysis. Am J Med. 2006 Dec;119(12):1005-12. doi: 10.1016/j.amjmed.2006.02.026. PMID: 17145239; PMCID: PMC4394901.

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Guerrero FA, Medina GM. Effect of a medicinal plant (Passiflora incarnata L) on sleep. Sleep Sci. 2017 Jul-Sep;10(3):96-100. doi: 10.5935/1984-0063.20170018. PMID: 29410738; PMCID: PMC5699852.

da Fonseca LR, Rodrigues RA, Ramos AS, da Cruz JD, Ferreira JLP, Silva JRA, Amaral ACF. Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential. ScientificWorldJournal. 2020 Jul 20;2020:6598434. doi: 10.1155/2020/6598434. PMID: 32765195; PMCID: PMC7387951.

Mao JJ, Xie SX, Keefe JR, Soeller I, Li QS, Amsterdam JD. Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial. Phytomedicine. 2016 Dec 15;23(14):1735-1742. doi: 10.1016/j.phymed.2016.10.012. Epub 2016 Oct 24. PMID: 27912875; PMCID: PMC5646235.

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Kim S, Jo K, Hong KB, Han SH, Suh HJ. GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. Pharm Biol. 2019 Dec;57(1):65-73. doi: 10.1080/13880209.2018.1557698. PMID: 30707852; PMCID: PMC6366437.

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Nutritional information

Nutrition information Per daily dose (1 tablet)
Valerian extract
of which valerenic acids
150 mg
0,6 mg
Passion flower extract of
 which flavonoids expressed as vitexins
150 mg
0,75 mg
Chamomile extract
of which apigenin
100 mg
0,3 mg
Escolzia extract
of which total alkaloids expressed as protopine
100 mg
0,2 mg
Saffr'Acti® saffron extract
of which Crocine
20 mg
0,6 mg
Gamma-Aminobutyric Acid (GABA) 100 mg
Melatonin 1 mg

Ingredients: bulking agents: cellulose, dicalcium phosphate, hydroxy-propyl methyl cellulose, cross-linked sodium carboxymethyl cellulose; dry extract of valerian (Valeriana officinalis L.) root 0.4% valerenic acids, dry extract of passion flower (Passiflora incarnata L. ) aerial parts with flowers 0.5% flavonoids expressed as vitexins, dry extract of chamomile (Matricaria chamomilla L.) flowers 0.3% apigenin, gamma-aminobutyric acid (GABA), extract of Eschscholzia (Eschscholzia californica Cham, aerial part) 0.2% total alkaloids expressed as protopine, anti-caking agents: magnesium salts of fatty acids, silicon dioxide; saffron extract Saffr'Activ® (Crocus sativus L. stigmas) 3% crocin, colouring agent: E 172; melatonin.

Directions: take 1 tablet a day with water just before going to bed.

Reviews (2)

Muhammad Shahzad 06/03/2023
Hi want to buy gkutathione sublingual from the company for Dubai.
Luca 16/02/2023
Formula interessante, sicuramente da provare

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