Liposomal IRON 20 Capsules


Liposomal IRON 20 Capsules

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Yamamoto® Nutrition Liposomal IRON is a food supplement providing LIPOFER™  microcapsules (microencapsulated liposomal iron) with vitamin C, folic acid and vitamin B12. Iron contributes to normal formation of red blood cells and haemoglobin and to normal oxygen transport in the body. The product is completed with the addition of vitamin C which increases iron absorption, folic acid which contributes to normal blood formation and vitamin B12 which contributes to the normal red blood cell formation.


Iron is an essential element for our health playing a primary role in immune function, for cardiovascular function and for congnitive development. However, iron deficiency is widespread and may have varying aetiology. "Anaemia" is a condition that results from a decrease in the concentration of haemoglobin in the blood. Data defined by the World Health Organization, which shows that there are one billion and 600 million inhabitants of the planet who are at risk of the consequences of this deficiency,  is significant. 700 million people globally are defined as "suffering from" anaemia. It is clear that this precious mineral is essential for the body, and becomes of further importance for those who practice very intense physical activity, being a major factor for the transport of oxygen to the skeletal muscle, which is carried out thanks to two molecules: haemoglobin and myoglobin. These two proteins have within them "sections", called the "haeme" group, which coordinate a bivalent iron (II) atom each: these haeme groups are the "reservoir" in which oxygen is stored. Athletes in particular endurance sports such as cycling, marathon runners, triathletes, athletics, cross fitters, etc. know that during performance, the body obviously requires a much greater amount of oxygen than when at rest and therefore tends to "consume" more haemoglobin and myoglobin.

Therefore, for the regeneration of these two molecules, our body needs constant iron. Little iron results in a poor production of red blood cells. Having few red blood cells is synonymous with poor oxygenation of every component of the organism and also with poor ability to "move air back" into the cells. The oxygen-carbon dioxide (cellular metabolism waste gas) exchange will never be optimum without an adequate number of efficient red blood cells. The main typical symptoms of an iron deficiency are: frequent tiredness, feeling of weakness, cold limbs, a weakened immune system, brittle nails and hair, mood swings, loss of mental "agility", with difficulty in concentrating. For endurance sports athletes, such as cyclists, marathon runners, triathletes, skiers, swimmers etc., it further translates into a potentially risky loss of performance and to feed states of profound overtiredness, with impaired recovery, in addition to harming the body's overall state of health. All these symptoms are related to the fact that the body does not have enough iron to produce haemoglobin, which transports oxygen to the main vital organs.

For many people, especially athletes, it is often not enough to introduce sufficient quantities of iron through diet alone, since they have an increased need and a greater loss through sweat and urine, so they are likely to need supplementation, since they may have lower iron stores, preventing their optimum performance. Before starting targeted iron supplementation, it is highly advisable to evaluate the actual iron deficiency, through a number of haematochemical parameters, because if there is no real need, there is risk of incurring problems due to iron buildup over time. The most recommended dosage is that of serum ferritin, which is the iron storage protein and its amount should not be less than 15-20 µg/l in adults and 12 µg/l in children. It is the iron of "store", that is the iron that has been assimilated by the organism but not necessarily used. Another fundamental parameter is the Sideraemia (or serum iron) which is the iron available in the blood plasma, which should be included in the parameters of 50-150mcg/dl. If the value is low, it means that the body has no iron available. When these parameters fall below the physiological values ??as is particularly common in athletes, iron supplementation can be very helpful in restoring iron reserves and oxygenation of the physiological blood. The iron forms most commonly prescribed and used in cases of deficiency are: ferrous sulphate, ferric citrate, iron D-gluconate. However, all these forms have varying rates of absorption and often have multiple side effects: stomach ache, abdominal pain, nausea, constipation or diarrhoea and dark stools. The side effects can sometimes even require discontinuation of taking supplements.

Our Liposomal IRON, is a supplement based on LIPOFER ™, a compound of ferric pyrophosphate that uses "liposomal" vehicle technology, i.e. it is incorporated into a phospholipid membrane, a sort of protective "shell", and, compared to other oral formulations, it allows better gastrointestinal absorption with a higher bioavailability of the mineral with lower incidence of side effects. Under normal conditions, generally only 15-20% of orally administered iron is absorbed due to an inherent limit in the availability of specific carriers at the duodenal level, so it is not worthwhile increasing the dose taken (and it may even be harmful), because once the transport capacity of the carriers has been saturated, this would only achieve an increase in side effects. We need very little of this essential mineral element to our body, but that "small portion" must be bioavailable.

The reason it has become renowned within the medical field in recent years is to do with the fact that thanks to the sophisticated technology of liposomal microencapsulation, liposomal iron leaves the gastric environment intact and is absorbed within the entire intestine (not only at the duodenal level). In this way it will arrive intact "at its destination" without disturbing the gastrointestinal mucosa. The scientific literature has shown that, thanks to liposomal technology, absorption of liposomal pyrophosphate iron is 3.5 times greater than free iron pyrophosphate, 2.7 times higher than iron sulfate and 4.1 times higher compared to iron gluconate. In addition, folic acid is added to make optimal use of the iron conveyed at the cellular level, in addition to vitamin C and Vitamin B12, which further favours optimum bioavailability.

Liposomal IRON belongs to the latest-generation of iron food supplements, which makes it effective without the risk of unwanted side effects. It is aimed at all people with a real iron deficiency, as in cases of anaemia in athletes and non-pathological sideropaenic anaemia.

*Recommended dose (unless otherwise directed by a doctor): 1 capsule per day, to be taken at any time of the day.

Nutritional information

20 capsules
Mean analysis
Per daily dose 1 capsule
  Per daily dose (1 capsule)
Iron LIPOFER™ microcapsules
Vitamin C
Folic acid
Vitamin B12
15 mg (108% RI*)
80 mg (100% RI*)
200 µg (100% RI*)
1 µg (40% RI*)
*RI: reference intake

Ingredients: LIPOFER™ microcapsules [microencapsulated ferric pyrophosphate (ferric pyrophosphate, corn starch, glazing
agent: sunflower lecithin)], L-ascorbic acid (vitamin C), capsule (gelatin, colour: titanium dioxide), bulking agent: cellulose
microcrystalline; anti-caking agents: magnesium salts of fatty acids, silicon dioxide; cyanocobalamin (vitamin B12), pteroylmonoglutamic acid (folic acid).

LIPOFER™ microcapsules is a registered trademark of Lipofoods.

Directions: take 1 capsule a day with water.


WARNINGS: do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied diet. A varied and balanced diet and a healthy lifestyle are important. Keep out of the reach of young children. Keep in a cool and dry place. Avoid exposure to heat sources and sunlight. Do not dump after use.

Reviews (1)

USER: 41256
05/11/2019 17:23
Ho provato questo integratore visto che già conoscevo Yamamoto per i suoi ottimi prodotti sportivi e devo dire che sono rimasto più che soddisfatto. La composizione è perfetta per chi come me soffre di anemia e la qualità degli ingredienti è top, come sempre. Lo ricomprerò di sicuro.

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